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Pathways Recommended: PROTAC
Results for "

Gefitinib-based PROTAC 3

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123921
    Gefitinib-based PROTAC 3
    1 Publications Verification

    		 PROTACs EGFR Cancer
    Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively .
    <em>Gefitinib-based</em> <em>PROTAC 3</em>

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